Table 1.
Correlation of CEACAM 7 and CEA expression with clinicopathological characteristics of gastric carcinoma.
| Variables | CEACAM 7 | P value | CEA | P value | ||
|---|---|---|---|---|---|---|
| Negative (n = 100) |
Positive (n = 45) |
Negative (n = 81) |
Positive (n = 64) |
|||
| Gender | ||||||
| Male | 74(67.3%) | 36(32.7%) | 0.437 | 58(52.7%) | 52(47.3%) | 0.178 |
| Female | 26(74.3%) | 9 (25.7%) | 23(65.7%) | 12(34.3%) | ||
| Age (Years) | ||||||
| (means ± SD) | 59.8 ± 10.4 | 58.1 ± 13.3 | 0.608 | 60.3 ± 9.4 | 58.9 ± 12.9 | 0.512 |
| Location of tumor | ||||||
| Upper | 12(60.0%) | 8 (40.0%) | 0.601 | 9 (45.0%) | 11(55.0%) | 0.544 |
| Middle | 49(69.0%) | 22(31.0%) | 40(56.3%) | 31(43.7%) | ||
| Lower | 39(72.2%) | 15(27.8%) | 32(59.3%) | 22(40.7%) | ||
| Histology † | ||||||
| Well and Moderate | 56(80.0%) | 14(20.0%) | 0.006 | 43(61.4%) | 27(38.6%) | 0.741 |
| Undifferentiated | 44(58.7%) | 31(41.3%) | 38(50.7%) | 37(49.3%) | ||
| Lauren's classification | ||||||
| Intestinal | 56(77.8%) | 16(22.2%) | 0.023 | 39(54.2%) | 33(45.8%) | 0.683 |
| Diffuse | 44(60.3%) | 29(39.7%) | 42(57.5%) | 31(42.5%) | ||
| Depth of tumor | ||||||
| T1-T2 | 28(75.7%) | 9 (24.3%) | 0.307 | 20(54.1%) | 17(45.9%) | 0.797 |
| T3-T4 | 72(66.7%) | 36(33.3%) | 61(56.5%) | 47(43.5%) | ||
| Node metastasis | ||||||
| Negative | 59(72.8%) | 22(27.2%) | 0.257 | 37(67.3%) | 18(32.7%) | 0.031 |
| Positive | 41(64.1%) | 23(35.9%) | 44(48.9%) | 46(51.1%) | ||
| Lymphatic invasion | ||||||
| Negative | 44(75.9%) | 14(24.1%) | 0.143 | 35(60.3%) | 23(39.7%) | 0.375 |
| Positive | 56(64.4%) | 31(35.6%) | 46(52.9%) | 41(47.1%) | ||
| Venous invasion | ||||||
| Negative | 52(70.3%) | 22(29.7%) | 0.729 | 43(58.1%) | 31(41.9%) | 0.578 |
| Positive | 48(67.6%) | 23(32.4%) | 38(53.5%) | 33(46.5%) | ||
| Tumor Stage | ||||||
| I- II | 40(62.5%) | 24(37.5%) | 0.135 | 34(53.1%) | 30(46.9%) | 0.555 |
| III- IV | 60(74.1%) | 21(25.9%) | 47(58.0%) | 34(42.0%) | ||
NOTE: Pearson's X2 test was done to get P value except that Ages was compared by Student-T test. †Well = well differentiated carcinoma; moderately = moderately differentiated carcinoma; undifferentiated = poorly differentiated carcinoma, signet ring cell carcinoma, or mucinous carcinoma.