Table 1.

Criteria for studies in which simple indices of insulin resistance may be used.

	Study objectives
1.	Large clinical practice and epidemiological investigations [70].
2.	Where the assessment of direct IR is not required.
3.	Where the outcome of IR is of secondary interest [71].
4.	Where the requirements of reference techniques are not available e.g equipments, trained staff, enough budget.
5.	Where a new simple index is under evaluation [72,73].
6.	Investigating validity and pitfalls of simple indices in specific clinical conditions [41,57].

References have been provided as a study example: