Figure 4. Bmp7 functions to promote cell survival in the cloacal endoderm.

(A–B) Sagittal section of E12.5 wild type (A) and Bmp7 null (B) cloacal regions were processed for TUNEL assay, and nuclei stained with DAPI. (C) Graph presents percentage ratios of TUNEL-positive cells in the cloacal endoderm (CE) and genital mesenchyme (gm). Calculations were carried out as described in Methods. Student's t-test: *P<0.01. Scale bars: 50 µm.