Table 3.
Factors Associated with ADR-Related Hospitalizations in Older Veterans (n=678)
Variable | Adjusted OR | 95% CI | P value |
---|---|---|---|
Primary Independent Variable | |||
Number of regularly scheduled medications | |||
0–4 | 1.0 (Reference) | -- | -- |
5–8 | 2.85 | 1.03–7.85 | 0.04 |
≥ 9 | 3.90 | 1.43–10.61 | <0.01 |
Demographic Control Variables | |||
Age (years) | |||
≥ 85 | 1.0 (Reference) | -- | -- |
65–74 | 0.76 | 0.33–1.74 | 0.51 |
75–84 | 0.62 | 0.27–1.41 | 0.25 |
Female | 1.15 | 0.13–10.26 | 0.90 |
Race/Ethnicity | |||
White | 1.0 (Reference) | -- | -- |
Black | 0.86 | 0.40–1.84 | 0.69 |
Hispanic | 0.21 | 0.03–1.60 | 0.13 |
Unmarried | 0.71 | 0.41–1.20 | 0.20 |
Health-Status Control Variables | |||
Selim Physical Comorbidity Index | 1.01 | 0.87–1.18 | 0.86 |
Selim Psychiatric Comorbidity Index | 0.85 | 0.45–1.60 | 0.61 |
Access to Care Control Variables | |||
Non-exempt copayment status | 1.31 | 0.61–2.82 | 0.49 |
Geriatric Evaluation & Management clinic visit in previous year | 1.39 | 0.50–3.90 | 0.53 |
Number of primary care visits in previous year | |||
0–1 | 1.0 (Reference) | -- | -- |
2–4 | 1.20 | 0.53–2.74 | 0.66 |
5 | 0.62 | 0.25–1.54 | 0.30 |
Emergency Department visit in previous year | 1.09 | 0.57–2.08 | 0.80 |
Hospitalization in previous year | 1.24 | 0.60–2.58 | 0.57 |
Year of hospital admission | |||
2006 | 1.0 (Reference) | -- | -- |
2004 | 1.01 | 0.51–1.99 | 0.98 |
2005 | 0.68 | 0.38–1.23 | 0.20 |
Abbreviations: ADR: adverse drug reaction
Hosmer and Lemeshow Goodness-of-Fit Test: x2=12.46; df=8; p=0.13