Table 2.
The 10 most up- and down-regulated genes in DF-1 cells as determined by Ingenuity Pathway Analysis software
| The 10 most up-regulated genes | ||||
|---|---|---|---|---|
| ID | Symbol | Entrez Gene Name | Log Ratio | p-value |
| AB196971 | APCDD1 | adenomatosis polyposis coli down-regulated 1 | 4.75 | 4.68 × 10-8 |
| AJ131110 | TWIST2 | twist homolog 2 (Drosophila) | 4.61 | 3.93 × 10-9 |
| BX936211 | TMEM116 | transmembrane protein 116 | 4.26 | 9.58 × 10-10 |
| S64689 | MYH6 | myosin, heavy chain 6, cardiac muscle, alpha | 3.52 | 4.92 × 10-6 |
| AJ851540 | CARD11 | caspase recruitment domain family, member 11 | 3.51 | 1.66 × 10-8 |
| BX932923 | PLEK2 | pleckstrin 2 | 3.47 | 2.63 × 10-8 |
| CR523499 | OSGIN1 | oxidative stress induced growth inhibitor 1 | 3.43 | 5.04 × 10-9 |
| DQ129668 | COLEC10 | collectin sub-family member 10 (C-type lectin) | 3.19 | 1.81 × 10-7 |
| BX933215 | SOCS1 | suppressor of cytokine signaling 1 | 3.05 | 3.63 × 10-7 |
| CR407099 | VPS13B | vacuolar protein sorting 13 homolog B (yeast) | 3.03 | 3.44 × 10-6 |
| The 10 most down-regulated genes | ||||
| ID | Symbol | Entrez Gene Name | Log Ratio | p-value |
| X59284 | NOV | nephroblastoma overexpressed gene | -8.40 | 3.11 × 10-9 |
| AJ719388 | SLC25A4 | solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 4 | -7.69 | 1.22 × 10-10 |
| Y138247 | CDKN2B | cyclin-dependent kinase inhibitor 2B (p15, inhibits CDK4) | -7.68 | 2.75 × 10-10 |
| X80503 | ST3GAL1 | ST3 beta-galactoside alpha-2,3-sialyltransferase 1 | -7.26 | 4.67 × 10-9 |
| M64990 | PTGS2 | prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) | -6.78 | 1.11 × 10-10 |
| X935556 | CTHRC1 | collagen triple helix repeat containing 1 | -6.78 | 3.20 × 10-8 |
| M68514 | EPHA3 | ephrin receptor A3 | -6.73 | 5.89 × 10-9 |
| AJ719946 | MANSC1 | MANSC domain containing 1 | -6.65 | 5.66 × 10-8 |
| AJ251273 | CCK | cholecystokinin | -6.63 | 1.27 × 10-11 |
| Y049705 | MAB21L1 | mab-21-like 1 (C. elegans) | -6.44 | 2.26 × 10-10 |
Fold change (FC) values were indicated by log2. The highly differentially expressed genes were sorted. All genes were matched and verified with UniGene function of NCBI database.