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MAA adduction of human lung surfactant protein in vitro. Human surfactant protein D (SPD) and surfactant protein A (SPA) were purified from whole lung lavage fluid and chemically adducted with malondialdehyde and acetaldehyde as described in Methods. Purified SPD and SPA form hybrid aldehyde adducts similar to MAA-adducted bovine serum albumin (BSA).
