. 2011 Jun 11;33(2):183–190. doi: 10.1093/eurheartj/ehr192

Table 5.

Net reclassification index and clinical net reclassification index of various model comparisons

Model^a	Overall						Women						Men
	NRI %^b			Clinical NRI %^b			NRI %^b			Clinical NRI %^b			NRI %^b			Clinical NRI %
	Overall (95% CI)	Events	No events	Overall (95% CI)	Events	No events	Overall (95% CI)	Events	No events	Overall (95% CI)	Events	No events	Overall (95% CI)	Events	No events	Overall (95% CI)	Events	No events
ACRS vs. ACRS + CCA-IMT	7.6 (2.9, 13.0)	5.5	2.2	18.7 (11.0, 26.7)	8.2	10.5	8.2 (0.8, 16.5)	8.2	0.1	24.4 (8.7, 39.3)	9.9	14.6	6.2 (1.2, 14.5)	4.8	1.4	11.6 (5.9, 22.8)	6.3	5.2
ACRS vs. ACRS + A-CIMT	8.9 (4.1, 14.4)	6.7	2.2	21.4 (13.3, 28.8)	9.9	11.4	8.1 (−0.1, 14.8)	8.1	0.0	23.0 (8.3, 37.5)	8.4	14.6	9.5 (4.4, 18.0)	3.4	6.1	16.3 (9.6, 27.6)	9.0	7.3
ACRS + A-CIMT vs. ACRS + CCA-IMT	−1.2 (−4.3, 1.6)	−1.2	−0.1	1.4 (−2.2, 6.2)	−1.4	2.7	0.09 (−3.0, 4.8)	0.0	0.1	1.27 (−3.4, 12.5)	−1.4	2.7	−3.3 (−8.0, 1.4)	−2.0	−1.4	1.28 (−4.2, 6.8)	2.4	−1.1
FRS vs. FRS + CCA-IMT	16.2 (11.2, 21.9)	12.7	3.4	24.5 (18.2, 31.9)	13.6	11.0	6.3 (−1.7, 15.0)	6.4	−0.1	19.8 (6.8, 33.7)	5.3	14.5	10.6 (4.9, 18.7)	4.7	5.8	15.6 (9.1, 25.4)	9.7	5.9
FRS vs. FRS + A-CIMT	16.5 (11.6, 23.6)	12.8	3.7	25.6 (19.0, 34.0)	13.7	11.8	6.3 (−2.3, 14.4)	6.6	−0.4	18.6 (5.2, 32.8)	4.5	14.2	12.8 (7.0, 20.6)	6.8	6.1	19. 0 (12.1, 28.1)	13.4	5.7
FRS + A-CIMT vs. FRS + CCA-IMT	−0.35 (−4.7, 2.1)	−0.1	−0.3	2.64 (−2.1, 6.0)	−1.3	4.0	0.10 (−3.8, 4.6)	−0.3	0.2	4.9 (−1.2 12.2)	−0.5	5.3	−2.27 (−7.2, 2.9)	−2.0	−0.2	1.28 (−4.4, 6.8)	2.1	−1.4

ACRS, ARIC coronary risk score using traditional risk factors; FRS, Framingham risk score using traditional risk factors; A-CIMT, CIMT using all carotid artery segments; CCA-IMT, common carotid artery IMT; NRI, net reclassification index; C-NRI, clinical NRI.

^aAll IMT models also include plaque information.

^b‘Events’ = NRI or C-NRI among those who had an event and ‘No events’ = NRI or C-NRI among those who did not have an event.