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. Author manuscript; available in PMC: 2013 Jun 1.
Published in final edited form as: Inflamm Bowel Dis. 2011 Oct 12;18(6):1081–1091. doi: 10.1002/ibd.21898

Figure 1. Rolipram treatment slows epithelial cell shedding.

Figure 1

(A) 24 hour migration of BrdU labeled cells was quantified in mice treated with rolipram. *, P≥0.05 compared to untreated control mice. Values are mean±SEM of 3 separate experiments. (B) Micrographs of ileum of adult mice corresponding to panel A. Bars represent BrdU positive cells. (C) Acriflavin stained intestinal epithelium was wounded using a 2-photon laser (wounded area denoted with white arrow). Increased time to shedding was observed in rolipram-treated animals. Images were taken at 400×. Images are representative of 3–4 mice.