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. Author manuscript; available in PMC: 2013 Jun 1.
Published in final edited form as: Inflamm Bowel Dis. 2011 Oct 12;18(6):1081–1091. doi: 10.1002/ibd.21898

Figure 3. Elevated cAMP levels inhibit epithelial cell migration in vitro.

Figure 3

(A) Quantification of IEC-6 migration with increasing doses of forskolin for 18 hours. TGF-β [5ng/ml] served as a positive control for migration. (B) Representative images of wounded monolayers at time 0 and 18 hours after treatment. (C and D) Migration rate (µm/hour) of untreated cells (open circles) and cells treated with forskolin (solid box). Values are mean±SEM from 3–5 experiments. *, P≤0.05; **, P≤0.01 compared to untreated cells.