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. Author manuscript; available in PMC: 2013 Jan 10.
Published in final edited form as: J Control Release. 2011 Sep 16;157(1):103–111. doi: 10.1016/j.jconrel.2011.09.068

Figure 1.

Figure 1

Experimental setup. (A) A single oocyte was placed in ND96 solution. The femtosecond laser beam generated and trapped a single microbubble 500 µm horizontally from the oocyte. An ultrasound transducer assembly in an adjacent tank controlled and generated cavitation. Voltage-clamp measured the TMC of the cell in real time. A high speed camera was used to image the ultrasound-driven dynamic bubble activities. Inset: A microbubble generated by LIOB was trapped and then moved toward the oocyte by the 7 MHz ultrasound pulses. (B) Schematic illustration of the separation distance D between the cell membrane and a bubble (diameter of d).