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. Author manuscript; available in PMC: 2012 Jan 15.
Published in final edited form as: J Org Chem. 2005 Aug 5;70(16):6362–6368. doi: 10.1021/jo0508189

Table 2.

Substituent effect on the formation of [1,2,4]triazoles from symmetrical thioureas

graphic file with name nihms60552u2.jpg
R1 R2 % Yield
a 4-OMe-Phenyl H 89
b 4-Cl-Phenyl H 74
c 3,5-di-CF3-Phenyl H 36
d tert-Butyl H Urea
e Cyclohexyl H Urea
f n-Propyl H Urea
g Phenyl Me 68
h Phenyl Phenyl 12
i Phenyl H 73
j 4-OMe-Phenyl Me 77
k 3,5-di-CF3-Phenyl Me 60