. Author manuscript; available in PMC: 2012 Dec 20.

Published in final edited form as: Virology. 2011 Oct 13;421(2):114–118. doi: 10.1016/j.virol.2011.09.018

Table 1.

E6/E7 and E7 transgenic mice confer significantly higher rates of tumor and carcinoma incidence

		Phenotvpe	Histopathological Classification of Disease
Genotype	n	Overt Tumor	Normal	Papilloma	Atypia	Cancer
NTG	21	4 (19%)	16	0	3	2 (10%)
E6	33	6 (18%)	24	0	3	6 (18%)
E7	33	29 (88%)^*	2	0	3	28 (85%)^†
E6/E7	20	20 (100%)^*	0	0	3	17 (85%)^†

p<0.01 for E7 or E6/E7 tumors compared to E6 or NTG tumors

^†

p<0.01 for E7 or E6/E7 cancers compared to E6 or NTG cancers

P-values were calculated using two-sided Chi square test