Table 1.
Characterization of cardiac defects in wt and cTP mutants by MRI analysis
| wt (n = 7) | het (n = 5) | ko (n = 5) | |
|---|---|---|---|
| Heart position | |||
| Left-sided | 6 | 5 | 0 |
| Right-sided | 0 | 0 | 5 |
| Midline | 1 | 0 | 0 |
| Apex direction | |||
| Left | 6 | 0 | 0 |
| Right | 0 | 5 | 4 |
| Down | 1 | 0 | 1 |
| Atrial shape | |||
| No ASD, no RAI | 7 | 5 | 0 |
| ASD plus RAI | 0 | 0 | 5 |
| ICV drainage | |||
| Into RA | 7 | 5 | 0 |
| Into common atrium | 0 | 0 | 5 |
| PV drainage | |||
| Into LA | 7 | 5 | 0 |
| Into common atrium | 0 | 0 | 5 |
| AV junction | |||
| Normal | 7 | 5 | 0 |
| Abnormal | 0 | 0 | 5 |
| Ao exit | |||
| From LV | 7 | 5 | 0 |
| From RV | 0 | 0 | 5 |
| PA exit | |||
| From RV | 7 | 5 | 1 |
| From LV | 0 | 0 | 4 |
| TGA | 0 | 0 | 4 |
| DORV | 0 | 0 | 1 |