. 2011 Jul 11;7(3):414–422. doi: 10.5114/aoms.2011.23404

Table I.

Summary of sequences and cleavage sites of DNAzymes used

	DNAzyme sequence (5'-3')^a	RNA substrate sequence (5'-3')	Cleavage site (nt)
DRz1694	ATTCGCAggctagctacaacgaTGTCTTCGCCTT	AAGGCGAAGACAAUGCGAAU	1694
DRz1366	CTTGAGTTGAGggctagctacaacgaCGCAGTAAT	AUUACUGCGACUCAACUCAAG	1366
DRz5491	CATAGGCAcgcatgctaacacgaTGTCCGCTTCT

The 10-23 catalytic motifs of PS-DRzymes are indicated in lower case. The sequences of PS-DNAzymes for the target binding domains are in uppercase, which are designed to be complementary to mecR1 and blaR1 respectively and were all modified with phosphorothioates to increase nuclease resistance