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. 2011 Sep 2;7(4):613–618. doi: 10.5114/aoms.2011.24130

Table I.

Effect of 30-day treatment with nifedipine, verapamil and diltiazem on lipid peroxidation and antioxidant activities in sperm cells

Control Nifedipine Verapamil Diltiazem
MDA [nmol/ml] 7.8 ±0.39 10.3 ±0.20* 9.9 ±0.32* 10.7 ±0.28*
SOD [µmol/min] 3.8 ±0.18 2.7 ±0.29* 2.7 ±0.14* 3.1 ±0.22*
CAT [nmol/min] 11.8 ±1.02 7.8 ±0.58* 8.2 ±0.58* 7.2 ±0.37*
GSH [nmol/ml] 41.3 ±1.5 36.9 ±1.4 37.2 ±2.8 35.5 ±2.3

Values are expressed as mean ± SEM (n = 6);

*

p < 0.05, significantly different compared with control group; MDA – malondialdehyde, SOD – superoxide dismutase, CAT – catalase, GSH – reduced glutathione