Table III.

Clinical recommendations for drug interventions, in women [23, 24]

Recommendations	Class, level, generalizability index
Aspirin – high risk: administration of aspirin (75-162 mg daily) or clopidogrel, if there is a contraindication for aspirin, in high-risk women, unless contraindicated	I, A, 1
Aspirin-moderate risk: administration of aspirin (75-162 mg daily) in moderate risk women, provided that blood pressure has been adequately controlled, and its favourable effect exceeds the probability of bleeding from the gastrointestinal system	IIa, B, 2
β-Blockers: these drugs should be administered indefinitely in all women with a history of myocardial infarction, or with chronic myocardial ischaemia, unless contraindicated	I, A, 1
ACE inhibitors: these drugs should be administered in high risk women, unless contraindicated	I, A, 1
Angiotensin II receptor (AT1) inhibitors: these drugs should be administered in high risk women with clinically confirmed heart failure, or an ejection fraction of<40%, who cannot tolerate ACE inhibitors	I, B, 1