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. 2011 Dec 20;12:166. doi: 10.1186/1471-2350-12-166

Table 2.

Association between individual JAK2 SNPs, Metabolic Syndrome and related phenotypes

MS negative MS positive OR (IC 95%) p pa pb
rs7849191
TT vs. TC vs. CC 69 vs. 241 vs. 226 38 vs. 76 vs. 57 - 0.009 ns ns
CC + CT vs. TT 467 vs. 69 133 vs. 38 0.517 (0.333-0.803) 0.005 0.001 0.002
CC vs. CT + TT 226 vs. 310 57 vs. 114 0.686 (0.478-0.984) 0.048 0.011 0.034
rs3780378
TT vs. TC vs. CC 149 vs. 269 vs. 121 33 vs. 83 vs. 57 - 0.008 0.002 ns (0.096)
TT +TC vs. CC 418 vs. 121 116 vs. 57 0.589 (0.404-0.858) 0.006 0.001 0.007
TT vs. TC+ CC 149 vs. 390 33 vs. 140 0.617 (0.404-0.942) 0.027 0.020 0.022
HTG negative HTG positive OR (IC 95%) p pa pb
rs3780378
TT vs. TC vs. CC 139 vs. 250 vs. 108 48 vs.108 vs. 71 - 0.013 0.006 ns (0.082)
TT +TC vs. CC 389 vs. 108 136 vs. 71 0.610 (0.429-0.868) 0.007 0.002 0.011
TT vs. TC+ CC 139 vs. 358 48 vs. 179 - ns ns
HW negative HW positive OR (IC 95%) p pa pb
rs3780378
TT vs. TC vs. CC 145 vs. 257 vs. 118 41 vs.101 vs. 61 - 0.037 0.021 ns (0.082)
TT +TC vs. CC 402 vs. 118 142 vs. 61 0.683 (0.475-0.983) 0.044 0.016 ns (0.07)
TT vs. TC+ CC 145 vs. 375 41 vs. 172 0.655 (0.442-0.969) 0.037 0.033 ns (0.05)

a Age adjusted; b Age and BMI adjusted. MS = metabolic syndrome; HTG = Hypertriglyceridemia; HW = hypertriglyceridemic waist; ns = not significant.