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Aged animals perform poorly on a hippocampal dependent spatial learning task. Average latency to platform on day 1-3 of spatial acquisition testing via Morris water maze for young (closed circles) and aged rats (open circles) (A). Mean path length for young and aged rats on final day of testing (B). Data are presented as mean +/- SEM. *p < 0.01 compared with young. n = 20 per group.
