Table 3.
Patient characteristics of 37 cases prior to re-irradiation
| Patient Characteristics prior to re-BRT | n = 37 |
|---|---|
| Age (years) | |
| Median | 48 |
| KPS | |
| < 70 | 10 (27%) |
| ≥ 70 | 27 (73%) |
| ECOG | |
| 0-1 | 12 (32%) |
| 2 | 20 (54%) |
| 3-4 | 5 (13%) |
| Number of lesions | |
| 1-3 | 15 (40%) |
| > 3 | 22 (59%) |
| Primary status | |
| Controlled | 22 (59%) |
| Uncontrolled | 15 (40%) |
| Extracranial disease | |
| Brain only | 10 (27%) |
| Bone | 6 (16%) |
| Visceral | 19 (51%) |
| Other | 2 (5%) |
| RPA at re-BRT | |
| 1 | 12 (32%) |
| 2 | 10 (27%) |
| 3 | 15 (40%) |
| Chemotherapy at BM* | |
| Yes | 19 (51%) |
| No | 18 (49%) |
| Trastuzumab at BM* | |
| Yes | 6 (16%) |
| No | 31 (84%) |
* Refers to treatments given on or after the date of brain re-irradiation.
Abbreviations: re-BRT = re-irradiation, RPA = recursive partitioning analysis, KPS = karnofsky performance status, ECOG = eastern cooperative oncology group performance status, BM = brain metastasis