Figure 7. Induction of FXR target genes in ileum of WT and FXR-KO mice following acute EGCG treatment.
WT and FXR-KO mice were treated twice in one day with EGCG at 100 mg/kg for P.O. or at 25 mg/kg for I.P. The control groups were treated with vehicle. Intestinal mRNA levels of Fxr, Shp, Ibabp, and Fgf15 were determined by Q-PCR (n = 5 mice per group). An asterisk indicates P < 0.05 between the treatment and vehicle control group. Double asterisks indicate P < 0.01 between the treatment and vehicle control group.