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. Author manuscript; available in PMC: 2013 Feb 1.
Published in final edited form as: Neurobiol Dis. 2011 Oct 17;45(2):683–691. doi: 10.1016/j.nbd.2011.10.009

Figure 2.

Figure 2

Immunostaining for GAD65 in 2N and Ts65Dn DG. (A) Examples of immunofluorescence in 2N (left) and Ts65Dn (right) DG. Insert on top: Examples of immunofluorescence in IML at higher magnification. Note a tendency for a lower level of GAD65 in Ts65Dn. (B) Averaged values for the immunofluorescence intensity (arbitrary units) across the DG layers. Immunofluorescence was maximal in the outer molecular layer (OML), gradually reduced in the middle and inner molecular layers (MML and IML) and reached a minimum in the granule cell layer (GCL) and hilus. GCL’ and IML’ are the layers from the inferior (lower) blade of the DG. There was no significant difference between 2N and Ts65Dn DG layers (p > 0.2).