Fig. 3. Mdm2 activation of the ApoCIII promoter is abolished by SHP.
Transient transfection assays to determine the effect of SHP on Mdm2-mediated ApoCIII promoter activity in the absence or presence of p53. The experiments were performed as in Fig. 1. *p<0.01 vs. control (−) pcDNA3 group; ¥, ‡, §p<0.01 vs. HNF4α alone; ¶p<0.01 vs. p53 or SHP alone; £, †p<0.01 vs. p53 or Mdm2 alone.