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. Author manuscript; available in PMC: 2013 May 1.
Published in final edited form as: Int J Cancer. 2011 Aug 5;130(9):2003–2012. doi: 10.1002/ijc.26201

Fig. 2.

Fig. 2

IGFBP-6 inhibits angiogenesis in vitro. A) Tube formation assay was performed using HUVECs in the absence (panel a) or presence of IGFBP-6 (panel b: 500 ng/ml, and panel c: 1000 ng/ml) on culture dishes coated with BD Matrigel. Representative micrographs are shown. The effect of IGFBP-6 was quantified by measuring the average tube length (B) and node number (C). Results are expressed as a percentage of control (mean ± SE, n = 9. *, P < 0.05; **, P < 0.01 vs. control).