Table 4.
Comparison of hormone levels and the indices of ovarian function between the three groups.
| Group 1 | Group 2 | Group 3 | ||||
|---|---|---|---|---|---|---|
| Obese | Lean PCOS | Obese PCOS | ||||
| n | n | n | ||||
| Testosterone (nmol/L) | 53 | 2.03 ± 1.22 | 85 | 2.42 ± 1.51 | 67 | 2.94 ± 1.72## |
| Estradiol (pmol/L) | 37 | 0.39 ± 0.34 | 62 | 0.45 ± 0.47 | 40 | 0.72 ± 1.50 |
| Androstendione (nmol/L) | 17 | 11.58 ± 9.32 | 48 | 13.16 ± 9.33 | 33 | 13.34 ± 7.53 |
| DHEAS (mcmol/L) | 24 | 7.32 ± 4.29 | 60 | 9.24 ± 4.76 | 54 | 9.49 ± 4.98 |
| 17-OH-progesteron (nmol/L) | 16 | 2.50 ± 1.45 | 37 | 3.40 ± 2.93 | 38 | 3.49 ± 2.76 |
| LH (U/L) | 42 | 2.91 ± 1.85∧∧∧ | 74 | 5.74 ± 4.01 | 59 | 5.17 ± 4.25## |
| FSH (U/L) | 42 | 3.33 ± 1.94 | 76 | 3.40 ± 2.07 | 60 | 3.25 ± 1.81 |
| Prolactin (U/L) | 47 | 355.19 ± 235.88 | 54 | 388.45 ± 241.52 | 49 | 310.65 ± 184.77 |
| Cortisol 8 : 00 o'clock (nmol/L) | 52 | 405.14 ± 119.38 | 30 | 414.67 ± 156.03 | 41 | 392.35 ± 134.26 |
| Cortisol 22:00 o'clock (nmol/L) | 44 | 103.35 ± 97.67 | 15 | 111.37 ± 39.19 | 29 | 138.44 ± 113.19 |
| TSH (U/L) | 62 | 2.09 ± 0.99 | 39 | 2.02 ± 1.51 | 45 | 1.84 ± 1.17 |
| Presence of polycystic ovaries (PCO) (%) | 31 | 16.1%∧∧∧ | 85 | 84.7% | 62 | 79.0%### |
| Right ovary PCO (%) | 29 | 17.2%∧∧∧ | 74 | 87.8% | 56 | 67.9% ### |
| Left ovary PCO (%) | 29 | 13.8%∧∧∧ | 77 | 74.0% | 56 | 75.0%### |
| Right ovary volume (mL) | 18 | 6.99 ± 3.36∧∧ | 54 | 11.75 ± 6.16 | 37 | 10.37 ± 5.94 |
| Left ovary volume (mL) | 20 | 4.87 ± 3.06∧∧ | 54 | 9.18 ± 4.46*** | 35 | 11.13 ± 6.16 |
| Age of menarche (years) | 87 | 12.73 ± 1.66 | 86 | 13.05 ± 1.74 | 69 | 12.66 ± 1.62 |
| Length of menstrual cycle (days) | 44 | 29.55 ± 6.01∧∧∧ | 56 | 51.14 ± 23.12* | 30 | 40.87 ± 16.86## |
| Duration of menstrual bleeding (days) | 33 | 4.88 ± 2.84 | 44 | 4.95 ± 1.09 | 22 | 6.27 ± 5.55 |
| Rate of menstrual disturbances (%) | 107 | 39.3%∧∧∧ | 92 | 78.3% | 79 | 81.0%### |
| Regular menstrual cycle (%) | 106 | 65.1%∧∧∧ | 93 | 23.7% | 80 | 20.0%### |
| Oligiomenorrhea (%) | 104 | 28.8%∧∧∧ | 93 | 66.7% | 80 | 66.2%### |
| Hypermenorrhea (%) | 103 | 6.8% | 91 | 3.3% | 80 | 7.5% |
| Polymenorrhea (%) | 103 | 2.9% | 92 | 0% | 80 | 1.2% |
| Opsomenorrhea (%) | 103 | 3.9% | 92 | 3.3% | 80 | 2.5% |
| Amenorrhea (%) | 103 | 5.8% | 92 | 10.9% | 80 | 13.8% |
| Pregnancies | 98 | 0.59 ± 0.77∧∧∧ | 87 | 0.15 ± 0.45 | 81 | 0.42 ± 0.78 |
| Births | 97 | 0.51 ± 0.71∧∧∧ | 87 | 0.10 ± 0.34* | 81 | 0.31 ± 0.63 |
| Miscarriages | 89 | 0.07 ± 0.36 | 86 | 0.05 ± 0.26 | 78 | 0.08 ± 0.35 |
| Rate of infertility (%) | 40 | 25.0%∧ | 20 | 55.0% | 28 | 50.0% |
## P < 0.01; ### P < 0.001 between group 1 and group 3.
*P < 0.05; **P < 0.01; ***P < 0.001 between group 2 and group 3.
∧ P < 0.05; ∧∧ P < 0.01; ∧∧∧ P < 0.001 between group 1 and group 2.
n = number of patients.