Skip to main content
. Author manuscript; available in PMC: 2012 Sep 1.
Published in final edited form as: Future Virol. 2011 Nov;6(11):1339–1350. doi: 10.2217/fvl.11.107

Figure 2. Contributions of cytokines and neuronal cell destruction to the development of seizures.

Figure 2

Two opposing and complementary gradients represent the contributions of cytokines and neuronal cell destruction within the CNS to the development of seizures following viral infection. Seizures in H101-infected mice likely develop as a result of cytokines within the CNS, while seizures in GDVII-infected mice likely develop as a result of neuronal cell destruction. The other virus strains and mutants, such as the DApBL2M mutant, fall somewhere inbetween.