TABLE 2.

Dissociation constants (KD) measured in solution by NMR for the 10- and 15-residue-long histone tails methylated at lysine 4 bound to ING4(188–249)

Liganda	KDb
	μm
H315K4me0	370 ± 20
H310K4me0	274 ± 6
H315K4me1	1.6 ± 0.8
H310K4me1	34 ± 4
H315K4me2	2 ± 1
H310K4me2	9.2 ± 1.4
H315K4me3	3.9 ± 0.7
H310K4me3	3.0 ± 0.6
H310R2me2K4me3	19.2 ± 1.7
H310R2me2c	1400 ± 40

^aThe values for H3₁₅K4 peptides are from Ref. 13

^bThe fitting errors are indicated

^cMeasured from the CSP of C212 signal instead of Trp²³⁷ (see supplemental Fig. S4)