TABLE 6.
DIFFERENTIALLY EXPRESSED PROTEINS IN THE AQUEOUS HUMOR OF THE FIVE-YEAR-OLD BUPHTHALMIC RABBITS
| ACCESSION | PROTEIN | N PEPTIDES | N SCANS | N FREQUENCY/ TOTAL* | B PEPTIDES | B SCANS | B FREQUENCY/ TOTAL* | NORMALIZED LOG RATIO† | ADJUSTED P VALUE |
|---|---|---|---|---|---|---|---|---|---|
| P18287 | Apolipoprotein E (Apo-E) | 8 | 442 | 4/4 | 9 | 165 | 4/4 | −1.76107 | 0.000000 |
| P49065 | Serum albumin | 38 | 4328 | 4/4 | 49 | 7068 | 4/4 | 0.368113 | 0.000000 |
| P07489 | Transthyretin (prealbumin) | 11 | 268 | 4/4 | 14 | 180 | 4/4 | −0.91372 | 0.000000 |
| P19007 | Haptoglobin | 7 | 62 | 4/4 | 4 | 19 | 4/4 | −2.04576 | 0.000000 |
| P20058 | Hemopexin | 10 | 80 | 4/4 | 6 | 38 | 4/4 | −1.41349 | 0.000006 |
| Q9XSC5 | Clusterin (apolipoprotein J) (Apo-J) | 7 | 47 | 4/4 | 13 | 115 | 4/4 | 0.951412 | 0.001422 |
| Q28372 | Gelsolin (actin- depolymerizing factor) | 9 | 91 | 4/4 | 8 | 62 | 4/4 | −0.89309 | 0.002137 |
| P01885 | Beta-2-microglobulin | 2 | 18 | 4/4 | 2 | 53 | 4/4 | 1.218507 | 0.007178 |
| P80191 | Alpha-2-HS-glycoprotein (fetuin-A) | 4 | 39 | 4/4 | 5 | 21 | 4/4 | −1.23257 | 0.006957 |
*
Number of animals in which protein was detected/Total number of animals used (N=4, B=4).
†
Calculated from the ratio of the scans (B/N) adjusted to the ratio of the total scans for all proteins detected in the sample.