Table 1.
Observed drug resistance in new, previously-treated, and all TB cases from four different settings of Varanasi in North India
| Setting | Resistant to | ||||||||||||||
| Rifampicin | Isoniazid | Streptomycin | Ethambutol | MDR-TB | |||||||||||
| PDR | ADR | All | PDR | ADR | All | PDR | ADR | All | PDR | ADR | All | PDR | ADR | All | |
| No. (%) | No. (%) | No. (%) | No. (%) | No. (%) | No. (%) | No. (%) | No. (%) | No. (%) | No. (%) | No. (%) | No. (%) | No. (%) | No. (%) | No. (%) | |
| Department of Microbiology, IMS, BHU (30 CC) (n=100*) | 6(10.71) | 30(68.18) | 36(36.0) | 10(17.85) | 33(75.0) | 43(43.0) | 15(26.78) | 31(70.45) | 46(46.0) | 8(14.28) | 31(70.45) | 39(39.0) | 14(25.0) | 20(45.45) | 34 (34.0) |
| SS Hospital, IMS, BHU(30 CC)(n=135*) | 16(19.04) | 37(72.54) | 53 (39.25) | 18(21.42) | 38(74.50) | 56(41.48) | 24(28.57) | 40(78.43) | 64 (47.40) | 18 (21.42) | 36(70.58) | 54(40.0) | 12 (14.28) | 35 (68.82) | 47 (34.81) |
| TB Centre, Bhelupur(10 CC)(n=32*) | 7(35.0) | 7(50.0) | 14 (41.17) | 6(30.0) | 9(64.28) | 15 (44.11) | 6(30.0) | 9(64.28) | 15 (44.11) | 4(20.0) | 8(57.14) | 12 (35.29) | 5(25.0) | 7(50.0) | 12 (35.29) |
| TB Centre, Kabirchaura (20 CC)(n=34*) | 4(20.0) | 9(75.0) | 13 (40.62) | 7(35.0) | 8(66.66) | 15(46.87) | 7(35.0) | 9(75.0) | 16(50.0) | 7(35.0) | 6(50.0) | 13 (40.62) | 3(15.0) | 8(66.66) | 11 (34.37) |
| Weighted mean** | 10.55 | 28.08 | 38.7 | 12.81 | 29.72 | 42.69 | 17.12 | 29.94 | 47.39 | 11.97 | 27.84 | 39.85 | 10.74 | 23.54 | 34.9 |
*No. of culture-positive specimens;
**Weighted mean (almost similar to an arithmetic mean) for all the four settings used in the study;
ADR=Acquired drug resistance;
BHU=Banaras Hindu University;
IMS=Institute of Medical Studies;
PDR=Primary drug resistance; 10
CC=Primary Care Centre, 20
CC=Secondary-care Centre; 30
CC=Tertiary-care Centre;
Total no. of resistant strains=169;
Total no. of MDR strains=104