Skip to main content
. 2008 Sep 5;283(36):24469–24477. doi: 10.1074/jbc.M803212200

FIGURE 4.

FIGURE 4.

Effect of ATP concentration on DNA binding and helicase activities of Mcm4/6/7 in the absence and presence of Cdt1. DNA helicase (A) and DNA binding (B) activities of Mcm4/6/7 (40 ng) in the absence (lanes 2–6) or presence (lanes 7–11) of Cdt1 (30 ng) were examined with increasing concentrations of ATP. The level of DNA helicase activity, calculated as percent oligonucleotide displaced, is presented at various ATP concentrations. The stimulation of helicase activity by Cdt1 was more prominent at 10–13 mm ATP.