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Pseudopodial Rho/ROCK signaling, mRNA targeting, and local signaling. Pseudopodial Rho/ROCK activation will enhance the pseudopodial delivery of mRNAs coding for signaling molecules (such as M-Ras and Shp2) as well as the protein translation machinery defining a feedback loop that may promote pseudopodial Rho/ROCK signaling through local mRNA delivery and translation.
