FIGURE 3.

Variation in sensitivity of PKC isoenzymes to MSA. Purified PKC isoenzyme preparations were diluted in a buffer containing 1 mg/ml bovine serum albumin and incubated with 0.1–10 μm concentrations of MSA for 5 min at 30 °C. PKC activity was then determined using a neurogranin substrate polypeptide. The values are expressed as mean ± S.E. of triplicate estimations.