Table 2.
The networks of genes associated with the 38 genes differentially expressed in OTP group.
| ID | Molecules in Network | Score | Focus Molecules | Top Functions |
|---|---|---|---|---|
| 1 | ALPP, APC, ARHGEF4, ATP6V0A2, BUB1, CAPN2, CD96, CD3G, CDKN1A, CTNNBIP1, CYTH1, CYTIP, DDB2, DNM, DNM3, EGF, ERK1/2, FLT3LG, FNBP1, FYN, HIRA, HRAS, IL10, IL12 (complex), INO80B, IPCEF1, PAX7, PRDX6, prostaglandin E2, PVR, RAD23B, SENP2, SPDEF, SUMO1, TNFSF8 (includes EG:944) | 29 | 12 | Cellular Growth and Proliferation, Tissue Development, DNA Replication, Recombination, and Repair |
| 2 | 4-phenylbutyric acid, CDKN1A, CDKN1B, CEBPA, CLDND1, D-glucose, DERA, FABP2, GBE1, GCKR, GH1, GSK3B, HIF1A, Histone h3, HNF1A, HNF4A, INS1, JUN, KLHDC10, KLHL6, MIR30A (includes EG:407029), ORMDL1, PAAF1, PCNP, Pka, PPARD, PSMD1, PTPRN, REG1A, SPATS2L, SRPR, TGFB1, TP53 | 12 | 6 | Cellular Growth and Proliferation, Cell Cycle, Hepatic System Development and Function |
| 3 | ethanolamine kinase, ETNK1, norepinephrine | 3 | 1 | Carbohydrate Metabolism, Cardiovascular System Development and Function, Cell Cycle |
| 4 | ATAD2B, MIR27A (includes EG:407018), MIR27B (includes EG:407019), ZFP36 | 2 | 1 | Cancer, Reproductive System Disease, Cell Cycle |
| 5 | CIITA, GFI1, ZXDA, ZXDC | 2 | 1 | Cell Death, Connective Tissue Development and Function, Gene Expression |
| 6 | FAM13A, MIR124-1 (includes EG:406907), MIR124-2 (includes EG:406908), MIR124-3 (includes EG:406909) | 2 | 1 | Cellular Growth and Proliferation, Tissue Morphology, Cancer |
| 7 | MIR133A1, MIR133A2, MIR133A-1, MIR25 (includes EG:407014), TSGA14 | 2 | 1 | Cardiovascular System Development and Function, Organ Development, Cancer |
| 8 | Ap1 gamma, ARRB1, ARRB2, CLINT1, CLTC, SCYL2, ZFYVE9 | 2 | 1 | Cell Signaling, DNA Replication, Recombination, and Repair, Nucleic Acid Metabolism |