Table 3.
The networks of genes associated with the 82 genes differentially expressed in PCB group.
| ID | Molecules in Network | Score | Focus Molecules | Top Functions |
|---|---|---|---|---|
| 1 | ACTR5, AKIRIN1, BPTF, CEBPG, CRIPT, DSTN, EED, ERCC3, ERVK6, FN1, GH1, HNF4A, INO80, INO80B, INSIG1, JAZF1, LOC284393, MIR128-1 (includes EG:406915), MIR25 (includes EG:407014), PIN4, PPP2R4, RAD23B, RBBP4, retinoic acid, RFC3, RNASE4, RUVBL2, STAG1, TLK2, TP53, TROVE2, TSGA14, Vegf, WDR12, WRNIP1 | 33 | 16 | Cancer, Gastrointestinal Disease, Cellular Growth and Proliferation |
| 2 | AKR1C14, ALCAM, CCDC80, CCDC92 (includes EG:80212), CD6, CD96, CDK6, CYTH3, EIF5, EIF2S1, ERK1/2, FAM13A, FEZF1, HNRNPC, HRAS, Igh, KRAS, LGALS8, MIR124-1 (includes EG:406907), MIRLET7A (produces hsa-let-7a), NBL1, NOTCH2NL, PCOLCE, Pdgf, PGGT1B, PIF, PRKCZ, PVR, RAP1GDS1, RASGRP1, SMARCA4, STK24, TMEM109, VPS41, ZBTB24 (includes EG:9841) | 21 | 11 | Cancer, Developmental Disorder, Genetic Disorder |
| 3 | ARNT2, ATAD2B, C10ORF26, CD6, CDC42EP3, CLK4, ELOVL6, ERLIN2, FOXO4, FSTL1, GALNT4, GPN1, HEXA, IL12RB1, IL17D, IL17F, IL18BP, IL23A, IL23R, L-tyrosine, MIR205 (includes EG:406988), OVOL1, PDPN, POMC, SLC35A5, SOAT1, SUPT4H1, TGFB1, TLR2/TLR4, TNF, TNFAIP2, USP5, USP25, ZFP36, ZFP36L1 | 21 | 11 | Cellular Development, Cellular Growth and Proliferation, Hematological System Development and Function |
| 4 | AGT, Calmodulin, CCK, CNST, COL4A1, cyclic AMP, CYTH1, CYTH3, DDX3X, DNAJA2, ERRFI1, EWSR1, HMGXB4, HNRNPA1, HNRNPF, HNRNPH1, HNRNPM, IGFBP1, INS1, Lfa-1, LRCH4, MIRLET7B (includes EG:406884), P2RY12, Pde, PTBP1, RFC1, SLC38A9, SUV39H2, TNPO1, TRIM13, TWISTNB, UBE2V2, WASL (includes EG:8976), YBX1, ZCCHC14 | 20 | 11 | Behavior, Cell Cycle, Metabolic Disease |
| 5 | ASF1B, BRD2, CDK8, CDK12, CRSP5, DIO1, ETNK1, GTF2E1, H3F3B, H3F3C, HIRA, HIRIP3, Histone h3, Histone h4, MED4, MED12, MED16, MED17, MED20, MED22, MED23, MED25, MED27, MED30, MED7 (includes EG:9443), MSH5, norepinephrine, PAX7, PNN, RNA polymerase II, TCEA1, THRAP3, TRIM24, UBN1, ZCCHC17 | 14 | 8 | Gene Expression, Cell Signaling, Infection Mechanism |
| 6 | GBGT1, globoside alpha-N-acetylgalactosaminyltransferase, lipid | 2 | 1 | Lipid Metabolism, Small Molecule Biochemistry, Molecular Transport |
| 7 | GTF3C1, POLA2, PRPF38A | 2 | 1 | Gene Expression, Molecular Transport, Protein Trafficking |