Figure 3.
Comparison of antiretroviral effects of various formulations of IDV, RTV, ATV, and EFV as measured by reverse transcriptase (RT) activity.
Notes: Monocyte-derived macrophages (MDM) were treated with 100 μM of nanoparticles for 8 hours. MDM were infected with HIV-1ADA on days 1, 5, 10, and 15 post-loading and cultured for 10 days after infection. Medium was removed and RT activity was measured by 3H-TTP incorporation. Data are normalized to activity in HIV-1 infected untreated cells cultured in parallel. Data represent mean ± SEM for n = 4 determinations per treatment.