Table 3.

Estimated effects and coefficients for MPS and DLR (coded units)

Term	MPS					DLR
	Net effect	Regression coefficient	Standard error	Standardized effect (t)	P	Net effect	Regression coefficient	Standard error	Standardized effect (t)	P
Constant		369.55	5.819	63.51	0.0000		18.84	0.2488	75.75	0.0000
X1	37.27	18.64	5.819	3.20	0.0852	−30.82	−15.41	0.2488	−61.94	0.0003
X2	−118.10	−59.05	5.819	−10.15	0.0096	30.76	15.38	0.2488	61.84	0.0003
X3	124.70	62.35	5.819	10.72	0.0086	1.67	0.83	0.2488	3.35	0.0787
X4	−41.66	−20.83	5.819	−3.58	0.0699	−4.12	−2.06	0.2488	−8.27	0.0143
X5	−77.75	−38.88	5.819	−6.68	0.0217	5.05	2.53	0.2488	10.15	0.0096
X1 × X2	−4.92	−2.46	5.819	−0.42	0.7134	−25.97	−12.99	0.2488	−52.21	0.0004
X1 × X3	308.94	154.47	5.819	26.55	0.0014	−1.27	−0.64	0.2488	−2.56	0.1245
X1 × X4	130.78	65.39	5.819	11.24	0.0078	7.68	3.84	0.2488	15.43	0.0042
X1 × X5	−28.31	−14.15	5.819	−2.43	0.1355	−5.59	−2.79	0.2488	−11.23	0.0078
X2 × X3	53.99	27.00	5.819	4.64	0.0435	6.08	3.04	0.2488	12.22	0.0066
X2 × X4	−187.11	−93.56	5.819	−16.08	0.0038	−1.70	−0.85	0.2488	−3.14	0.0764
X2 × X5	154.52	77.26	5.819	13.28	0.0056	2.89	1.45	0.2488	5.82	0.0283
X3 × X4	17.56	8.78	5.819	1.51	0.2703	−3.75	−1.87	0.2488	−7.53	0.0172
X3 × X5	−3.20	−1.60	5.819	−0.27	0.8094	5.12	2.56	0.2488	10.30	0.0093
X4 × X5	−149.64	−74.82	5.819	−12.86	0.0060	−4.49	−2.25	0.2488	−9.03	0.0121

Notes: FA-CS concentration (X₁), Oli-A concentration (X₂), mass ratio of FA-CS to TPP (X₃), TPP concentration (X₄), and crosslinking time (X₅).

Abbreviations: MPS, mean particle size; DLR, drug loading rate.