Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
The indicated Egr2 binding sites were cloned upstream of a luciferase reporter gene and were transfected into B16/F10 cells along with increasing amounts (25 or 50 ng) of Egr2. Fold induction was calculated relative to the reporter activity in the absence of Egr2 for each construct. Id4 was activated 2.85- and 2.5-fold, respectively. Means and standard deviations for 6 independent assays are shown (for Mag, n=4).
