Table 1.
Baseline characteristics of (A) families for the primary sample of Indian multicase VL families, and (B) the Indian case-control cohorts
| (A) Family Structure | Number* |
|---|---|
| No families | 137 |
| No nuclear families | 176 |
| Nuclear families with 1 affected sib | 63 |
| Nuclear families with 2 affected sibs | 95 |
| Nuclear families with 3 affected sibs | 14 |
| Nuclear families with 4 affected sibs | 2 |
| Nuclear families with 5 affected sibs | 2 |
| No affected offspring | 313 |
| No affected parents | 63 |
| Total No affected individuals | 394 |
| Total No individuals | 836 |
| (B) Case-Control Sample | Number |
| Cases (no.) | 958 |
| Male | 571 |
| Female | 387 |
| Mean age at study encounter ± SD (yr) | 31.2 ± 16.7 |
| Range | 3-73 |
| Mean age at onset of VL ± SD (yr) | 26.8 ± 15.3 |
| Religious Group (no.) | |
| Hindu | 850 |
| Muslim | 108 |
| Controls (no.) | 1015 |
| Male | 570 |
| Female | 445 |
| Mean age at study encounter ± SD (yr) | 31.8 ± 15.9 |
| Religious Group (no.) | |
| Hindu | 885 |
| Muslim | 130 |
* Numbers are given for the individuals with DNA available for genotyping