Table 2.
Details of polymorphisms genotyped and the minor allele frequency (MAF) of variants in the Indian study population
| SNP Identity | Location | Amino Acid Change | Physical Position1 (bp) | Alleles2 | Strand | MAF |
|---|---|---|---|---|---|---|
| CXCR2_rs4674259 | 5'UTR | - | 218991005 | T/C | - | 0.43 |
| CXCR1_rs2234671 | Exon1 | S276T | 219029108 | G/C | - | 0.16 |
| CXCR1_rs3138060 | Intron1 | - | 219031500 | C/G | - | 0.12 |
1 Physical positions of markers are given according to Build 37.1 of the human genome; 2Major > minor alleles for this Indian population; All 3 SNPs were in HWE in both unaffected founders of families and in controls for the replication study.