Table 4.

Population-based association analysis between CXCR1/CXCR2 and VL

Common Designation	Allele	Affected	Unaffected	OR	L95	U95	P-values
CXCR2_rs4674259	T	840/1036	816/1160	1.15	1.01	1.31	0.027
CXCR1_rs2234671	G	286/1592	321/1657	0.92	0.77	1.10	0.384
CXCR1_rs3138060	C	197/1685	252/1732	1.25	1.02	1.53	0.028

Logistic regression analyses under an additive model for the replication sample of VL cases and controls. OR = odds ratio; L95 and U95 are lower and upper 95% confidence intervals. Allele counts are shown for minor/major allele for affected and unaffected individuals. Bold indicates associations significant at nominal P ≤ 0.05. The corrected P-value required to achieve significance taking account of 3 independent SNPs is P ≤ 0.017.