Table 1. Lead Boronic Acids.

Boronic Acid	Glucose Binding Affinity (M−1)	Cell Survival (80 nM) (%)	PCC(80 nM)
4-aminocarbonylphenyl boronic acid	45	97	0.01
3-N,N-dimethylamino phenyl boronic acid	357	86	−0.04
4-propylphenylboronic acid	303	202	−0.07
2,4-dichlorophenyl boronic acid	58	81	0.09
4-hydroxyphenyl boronic acid	80	198	−0.01
2,4-ditertbutoxypyrimidin-5-yl-boronic acid	608	90	0.03

The binding constants (M⁻¹), HeLa Cell Survival (%)** and PCC** values for the lead boronic acids (** Values shown are for HeLa cells incubated for 2 hrs. at 37°C with 80 nM concentration of the compounds).