Table 1.
Trial design | Parallel (n = 236) |
Other * (n = 27) |
---|---|---|
Journal type | ||
Specialty | 144 (61%) | 11 (41%) |
General medical | 92 (39%) | 16 (59% |
Funding | ||
Solely industry | 40 (17%) | 1 (4%) |
Part industry | 43 (18%) | 2 (7%) |
Non industry | 126 (53%) | 20 (74%) |
None | 5 (2%) | 2 (7%) |
Unknown | 22 (9%) | 2 (7%) |
CONSORT endorsing journal | ||
Yes | 210 (89%) | 27 (100%) |
No | 26 (11%) | 0 (0%) |
Top 5 common specialty fields | ||
Paediatrics 34 (14%) | Paediatrics 10 (34%) | |
Cardiology 29 (12%) | Cardiology 2 (7%) | |
Psychiatry 20 (9%) | Psychiatry 2 (7%) | |
Infectious diseases 20 (9%) | Infectious diseases 2 (7%) | |
Oncology 17 (7%) | Oncology 1 (3%) | |
Intervention | ||
Drug | 116 (49%) | 6 (22%) |
Surgery/procedure | 46 (20%) | 3 (11%) |
Counselling/lifestyle | 64 (27%) | 15 (56%) |
Equipment | 10 (4%) | 3 (11%) |
Study centres | ||
Single | 72 (31%) | 4 (15%) |
Multiple | 137 (58%) | 20 (74%) |
Unclear | 27 (11%) | 3 (11%) |
Number of study groups | ||
2 | 187 (79%) | 20 (74%) |
3 | 36 (15%) | 2 (7%) |
4 | 11 (5%) | 3 (11%) |
> 4 | 2 (1%) | 2 (7%) |
Sample size | ||
Median (IQR) | 213 (101 to 476) | 529 (130 to 2243) † |
10 to 90 percentile | 50 to 1217 | 56 to 61280 |
* Cluster n = 16; Crossover n = 4; Factorial n = 4; Split Body n = 3
† Sample size not reported for 1 cluster trial