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. 2012 Jan 17;7(1):e29865. doi: 10.1371/journal.pone.0029865

Figure 5. A critical period for the expression of the interference between LTP and LTD.

Figure 5

Absence of intracompartmental interference between strong LTP (apical pathway S2, bottom red trace) and strong LTD (apical pathway S1; top red trace) with a 90 min time interval between inductions. The expression of control (unpaired) strong LTD (top) and strong LTP (bottom) is shown in the gray traces. Compare with the intracompartmental interference observed with a 45 min time interval between inductions (Fig. 2B). Also compare the interference observed with a 15 min time interval and with a 45 min time interval between inductions across dendritic compartments (e.g. Fig. 3D vs. Fig. 3A). Each independent data set was obtained from 6 mice. S1 and S2 represent independent afferents synapsing on the apical dendritic compartment.