Table 1.
Effect of LPS on the release of cytokines by BMECs.
| Treatment | ||
|---|---|---|
| Cytokine (pg/mL) | Control | LPS 100 μg/mL |
| GM-CSF | 4.8 ± 3.1 | 160.0 ± 21.7** |
| IFN-γ | 4.4 ± 1.1 | 1.6 ± 0.6* |
| IL-1α | N.D. | N.D. |
| IL-1β | N.D. | N.D. |
| IL-2 | 1.1 ± 0.5 | N.D. |
| IL-4 | 0.9 ± 0.2 | 0.5 ± 0.2 |
| IL-6 | 6.7 ± 1.1 | 16.3 ± 2.3** |
| IL-10 | 2.3 ± 1.1 | N.D. |
| IL-12 (p70) | 1.6 ± 0.6 | 0.3 ± 0.3 |
| TNF-α | 0.5 ± 0.3 | 0.2 ± 0.2 |
BMECs were exposed to LPS (100 μg/mL) for 4 hr. Mean ± SEM (n = 7). N.D.: Not Detected. Statistical analysis was done by Student's t-test. * P < 0.05, ** P < 0.01 vs control.