Table 2.

Comparison of IL-1β,IL-6, TNF-αand OPG/RANK/RANKL levels among three groups

Variables	normal control (n = 20)	COPD with normal BMD (n = 30)	COPD with low BMD (n = 30)
IL-1β (fg/ml)	122.21 ± 35.14	186.83 ± 104.87†	192.94 ± 115.82†
IL-6(fg/ml)	354.37 ± 83.14	421.52 ± 125.78†	483.73 ± 110.38†‡
TNF-α (fg/ml)	193.09 ± 81.20	261.28 ± 96.09†	324.37 ± 141.29†‡
OPG(pg/ml)	236.50 ± 38.76	240.43 ± 65.77	257.97 ± 86.80
RANK(pg/ml)	82.28 ± 29.76	73.90 ± 50.41	2.24 ± 0.80 †‡

Data are mean (SD) unless otherwise stated.

†p < 0.05 compared with the normal control group.

‡p < 0.05 compared with the COPD with normal BMD group

COPD: chronic obstructive pulmonary disease, BMD: bone mineral density, IL: interleukin, TNF-α:tumor necrosis factor α, OPG: osteoprotegerin, RANK: receptor activator of NF-κB, RANKL: RANK ligand