Table 4. ITPase activities stratified by genotype, compared between control and HIV+-population.

	Control		HIV+
ITPA genotype	ITPase activity ± SD	% activity**	HIV+ ITPase activity ± SD	% activity**
Wild type	5.38±1.52	100	4.31±1.39*	80.1
c.94 C>A heterozygote	1.43±0.55	26.6	0.86±0.23*	16.0
c.124+21 A>C heterozygote	2.61±0.66	48.5	2.67±0.69	49.6
c.94C>A homozygote	0.00±0.05		0.03
c.124+21 C>C homozygote	1.81±0.19	33.6	1.99±0.73	37.0

ITPase activity in mol IMP/(mol Hb × h).

*p<0.001.

**% activity wild type: residual ITPase activity relative to wild type ITPase activity.