Table 2. Metabolic and inflammatory variables in circulation at initial of feeding (n = 8).

Variable	NC		HFD
	WT	KO	WT	KO
FFA (mmol/l)	0.70±0.03	0.93±0.04##	0.77±0.04	0.95±0.04**
TG (mg/dl)	38.93±1.92	41.50±1.73	36.48±1.46	40.93±1.71
TC (mg/dl)	129.40±6.99	133.81±5.63	133.11±5.77	135.21±5.69
HDL (mg/dl)	94.56±3.34	98.52±4.14	98.40±4.90	97.24±4.09
LDL (mg/dl)	17.67±0.64	19.30±0.80	17.67±0.53	19.51±0.80
leptin (pg/ml)	4185.08±133.44	4272.40±179.24	4062.63±179.68	4261.14±180.03
resistin (pg/ml)	878.84±42.93	901.80±37.38	779.53±29.21	887.01±37.42
Adiponectin (ug/ml/g)	1.18±0.06	1.31±0.05	1.17±0.05	1.27±0.05
IL-1β (pg/ml)	37.16±1.60	42.40±1.77	40.18±1.65	40.83±1.68
IL-2 (pg/ml)	11.62±0.63	10.80±0.44	10.98±0.52	11.31±0.45
IL-6 (pg/ml)	0.67±0.03	0.71±0.03	0.70±0.03	0.67±0.02
TNF-α (pg/ml)	2.21±0.10	2.14±0.09	2.33±0.08	2.25±0.08
MCP-1 (pg/ml)	21.24±0.66	23.10±0.96	23.06±1.03	22.72±0.93

Data are means ± SEM.

^## p<0.01 vs. WT mice fed an NC;

**p<0.01 vs. WT mice fed an HF.