Table 2. Genes identified as differentially expressed due to MOS in non-challenged control hosts¹.

Gene	Gene symbol	Gene ID	Fold change	P-value	Gene regulation by MOS2
Intestine
Immune response
Interleukin 3	IL-3	474356	1.05	2.98E-05	+
Toll-like receptor 3	TLR3	422720	1.04	0.00687	+
Toll-like receptor 2 precursor	TLR2-2	769014	1.03	0.00984	+
2′–5′ oligoadenylate synthetase A	OAS*A	395908	1.15	0.00000	+
Gallinacin-1 alpha	Gal-1	395841	1.03	0.00145	+
Metabolism
Phosphoenolpyruvate carboxykinase 1	PEPCK	396458	1.11	0.00007	+
Others
Myosin, heavy polypeptide 7, cardiac muscle	MYH7	395350	1.04	0.01797	+
Secreted protein acidic cysteine-rich	SPARC	386571	0.94	0.00023	−
Myosin, heavy chain 11, smooth muscle	MYH11	396211	0.87	0.00000	−
Heat shock 10 kDa protein 1	HSPE1	395948	0.90	0.00057	−
Myosin light polypeptide 9 regulatory	MYL9	396215	0.93	0.00117	−
Atrial natriuretic factor precursor	NPPA	395765	1.05	0.00005	+
Iron regulatory protein 1	IRP1	373916	0.92	0.00000	−
Liver
Immune response
Interleukin 13 Receptor Alpha 2	IL13RA2	422219	1.05	0.00002	+
Signal transducer and activator of transcription 2	STAT2	6773	0.97	0.02042	−
Putative CXCR1 isoform I and II (IL-8 receptor)	CXCR1	430652	1.07	0.00018	+
CD3 glycoprotein	CD3D	396518	1.04	0.00010	+
Metabolism
Enoyl-CoA hydratase	EHHADH	424877	0.95	0.01192	−
Protein phosphatase 1	PPP1R8	419564	0.97	0.04035	−
Phosphopyruvate hydratase	ENO2	395689	1.05	0.00362	+
Malic enzyme 1	ME	374189	0.96	0.05583	−
Others
Deiodinase Type 2	DIO2	373903	1.05	0.02708	+
Potassium voltage-gated channel shaker-related subfamily No 3	KCNA3	404303	0.95	0.00649	−
Skeletal muscle
Others
NK2 transcription factor related locus 5	NKX2-5	396073	1.18	0.00000	+
Desmin	DES	395906	0.89	0.00011	−

¹Control hosts: MOS-fed chickens v/s VIRG-fed chickens; The complete raw data have been deposited in the Gene Expression Omnibus (GEO) database, www.ncbi.nlm.nih.gov/projects/geo (accession no. GSE28959).

²+: up-regulated genes by MOS; −: down-regulated genes by MOS.