Table 5. Genes identified as differentially expressed due to LPS between MOS- and antibiotic-fed hosts1.
| Gene | Gene symbol | Gene ID | Fold change | P-value | Gene regulation by MOS2 |
| Intestine | |||||
| Immune response | |||||
| Interleukin 3 | IL-3 | 474356 | 1.03 | 0.00871 | + |
| Interleukin 10 | IL-10 | 428264 | 0.96 | 0.00028 | − |
| Toll-like receptor 3 | TLR3 | 422720 | 0.96 | 0.00053 | − |
| Zinc finger CCCH-type containing 15 | ZC3H15 | 423992 | 0.96 | 0.00100 | − |
| 2′–5′-oligoadenylate synthetase A | OAS*A | 395908 | 0.84 | 0.00000 | − |
| Gallinacin-1 alpha | Gal-1 | 395841 | 0.98 | 0.03227 | − |
| Others | |||||
| Actin alpha 2 smooth muscle aorta | ACTA2 | 423787 | 0.94 | 0.00017 | − |
| Heat shock 10 kDa protein 1 | HSPE1 | 395948 | 0.92 | 0.00756 | − |
| Liver | |||||
| Immune response | |||||
| Signal transducer and activator of transcription 2 | STAT2 | 6773 | 1.03 | 0.02089 | + |
| Metabolism | |||||
| UDP Glucose Pyrophosphorylase 2 | UGP2 | 373900 | 0.92 | 0.00009 | − |
| ATP citrate lyase | ACLY | 395373 | 0.93 | 0.00017 | − |
| Phosphopyruvate hydratase | ENO2 | 395689 | 0.91 | 0.00000 | − |
| Malic enzyme 1 | ME1 | 374189 | 0.92 | 0.00012 | − |
| ATP citrate synthase | CS | 1431 | 1.11 | 0.00000 | + |
| 5′-AMP-activated protein kinase gamma-2 | PRKAG2 | 420435 | 1.05 | 0.00290 | + |
| Others | |||||
| Iroquois homeobox protein 1 | IRX1 | 374185 | 1.06 | 0.00268 | + |
| Endothelial PAS domain protein 1 | EPAS1 | 395596 | 1.09 | 0.00158 | + |
| Potassium voltage-gated channel shaker-related subfamily No 3 | KCNA3 | 404303 | 1.07 | 0.00045 | + |
| Skeletal muscle | |||||
| Others | |||||
| NK2 transcription factor related locus 5 | NKX2-5 | 396073 | 1.14 | 0.00000 | + |
1
LPS-challenged hosts: MOS-fed chickens v/s VIRG-fed chickens; The complete raw data have been deposited in the Gene Expression Omnibus (GEO) database, www.ncbi.nlm.nih.gov/projects/geo (accession no. GSE28959).
2
+: up-regulated genes by MOS; −: down-regulated genes by MOS.