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. 2012 Jan 17;7(1):e30285. doi: 10.1371/journal.pone.0030285

Figure 1. Effect of mepyramine and JNJ 7777120 on BAL-fluid cellularity.

Figure 1

Mice were sensitized to, and provoked with, OVA and treated with DMSO, mepyramine, JNJ 7777120, or mepyramine plus JNJ 7777120 either 30 min before each provocation cycle (A) or 30 min before and 2 h after each injection for sensitization (B). As control, mice were sensitized with PBS (sham), provoked with OVA, and treated with DMSO. Cells in BAL-fluids, collected 24 h after the final challenge, were differentially counted. Data shown are means ± SD (n(sham) = 3, n(DMSO) = 7, n(mepyramine, JNJ 7777120, or mepyramine+JNJ 7777120) = 8; *, p≤0.05; **, p≤0.01; ***, p≤0.005).