Table 2. Experimental groups of mice.
group | n | sensitization | provocation | treatment |
sham | 3 | PBS | Ova | DMSO |
DMSO | 7 | Ova | Ova | DMSO |
mepyramine | 8 | Ova | Ova | mepyramine |
JNJ 7777120 | 8 | Ova | Ova | JNJ 7777120 |
mepyramine + JNJ 7777120 | 8 | Ova | Ova | mepyramine +JNJ 7777120 |
Mice, divided into the five groups indicated on the left, were either sham-sensitized with PBS or sensitized with OVA. Provocation was carried out by application of OVA in a nebulized form. Mice were treated either during sensitization or during provocation with DMSO (sham; DMSO) or with mepyramine and/or JNJ 7777120.